How Epitalon works
A peptide with telomerase effects in cells, but no proof that people live longer.
Also called: Epithalon, Epithalone, AEDG, Ala-Glu-Asp-Gly.
Khavinson bioregulator peptides · Synthetic pineal tetrapeptide studied in telomere and circadian models.
In cells, Epitalon can change telomerase and other ways cells maintain chromosome ends, called telomeres. Small human studies also found changes in melatonin-related markers. These findings do not show that people live longer or sleep better.
- Telomerase and ALT pathways: Telomere-maintenance changes seen in normal and cancer cell cultures.
- Melatonin and clock-gene markers: Small human studies show marker changes; clinical sleep effects remain unproven.
Half-life: No reliable human half-life or clearance study was found.
Related to Epitalon
- Pinealon: A peptide with unproven brain benefits and no established injection dose.
- Thymalin: A calf thymus extract studied for immune problems, with uncertain safety and product identity.
- Thymogen: A Russian peptide used for immune problems, with negative cancer trials.
- Vesugen: An experimental blood-vessel peptide with unclear benefits and poorly defined safety.
- Cortagen: A four-amino-acid brain peptide backed mainly by animal work and unverified patent claims.
- Ipamorelin: An experimental peptide that triggers growth hormone release.
Sources
- 503B Bulk Drug Substances List, FDA · FDA · 2026
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act, FDA · FDA · 2026
- Bulk Drug Substances Used in Compounding Under Section 503A of the FD&C Act, FDA · FDA · 2026
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks, FDA · FDA · 2026
- Federal Register: nonbinding draft HHS interim policy, October 30 2026, 2026
- GenoGenix LLC - 718739 - 01/20/2026, FDA · FDA · 2026
- HHS 503A peptide interim enforcement policy and conditions, October 30 2026, 2026
- July 23-24, 2026, Meeting of the Pharmacy Compounding Advisory Committee – FDA Briefing Document for Epitalon-Related Bulk Drug Substances (Epitalon (free base) and Epitalon acetate), FDA · 2026
- Peptide products, Therapeutic Goods Administration · TGA · 2026
- Risks of buying peptide products online, Therapeutic Goods Administration · 2026
- Sepsis, NHS · 2026
- The 2026 Prohibited List, World Anti-Doping Agency · WADA · 2026
- Therapeutic Goods (Poisons Standard—October 2026) Instrument 2026, Australian Government · Australian Government · 2026
- Think twice before injecting peptides bought online: unauthorized products can seriously harm you, Health Canada · Health Canada · 2026
- Anaphylaxis, NHS · NHS · 2023
Sources checked: 2026-10-18.
Information only, not medical advice. Peptifacts does not sell anything and does not link to sellers.