What does SLU-PP-332 do? Benefits and evidence

An exercise-mimicking research chemical with mouse benefits and no human dosing trials.

Also called: SLU PP 332, SLUPP332, SLUPP-332.

Exercise mimetics · Pan-estrogen-related receptor (ERRα/β/γ) agonist · Evidence: Animal studies only.

SLU-PP-332 is a small molecule, not a peptide. It activates cell switches involved in energy use and improved endurance and fat metabolism in mice. No published study has dosed people, and no human trial was registered in this search. Oral absorption is poor in preclinical work. Human benefits, safe doses and long-term harms are unknown.

  • In mice, it increased how long they could run on a treadmill. (animal)
  • In mice with obesity, it reduced fat gain. (animal)
  • Some users report easier cardio or more training capacity, others no effect; no study has tested it in people. (Reported by users)

Uses in the sources

  • Users report easier cardio or more training capacity; controlled human benefits are unproven. (Reported by users) (source)
  • Users report adding it during weight loss. The controlled fat-loss evidence comes from mice. (Reported by users) (source)
  • Used online for more energy; some reports instead describe fatigue or no benefit. (Reported by users) (source)

Related to SLU-PP-332

Sources

Sources checked: 2026-10-18.

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