SLU-PP-332 side effects and risks
An exercise-mimicking research chemical with mouse benefits and no human dosing trials.
Also called: SLU PP 332, SLUPP332, SLUPP-332.
Exercise mimetics · Pan-estrogen-related receptor (ERRα/β/γ) agonist · Evidence: Animal studies only.
Reported side effects
- Sweating or feeling hot: community reports: Reported online; no measured incidence., moderate. Stop and seek assessment if overheating, weakness or confusion develops. (source)
- Fatigue or brain fog: community reports: Reported during higher dosing and after stopping; rates and cause unknown., moderate. Persistent or disabling symptoms need clinical assessment. (source)
- Trouble sleeping: community reports: No placebo controlled frequency estimate., moderate (source)
- Injection pain or irritation: Reported online; product and solvent contributions unknown., moderate. Hot, swollen or spreading redness needs urgent assessment. (source)
- Lightheadedness and glucose changes: Both high and low readings reported; one comment gave 2.6 mmol/L. No verified incidence., serious. Check glucose during symptoms; confusion or collapse needs emergency care. (source)
- Reduced libido: isolated high-dose report: One poster escalated to 500 mg/day orally; hormone injury was not confirmed., moderate (source)
- Menstrual or breast changes: isolated report: One female commenter; no hormone tests or causal confirmation., moderate (source)
- Nausea during multi-drug use: One tesamorelin combination report; cause uncertain., moderate (source)
- Infection or serious allergy from unregulated injections: General unapproved injection risk; no SLU PP 332 specific rate., serious (source)
Stop and get help if
- Throat or tongue swelling, wheeze or trouble breathing: Stop exposure and call emergency services now; use prescribed adrenaline if available.
- Chest pain with breathlessness, sweating or faintness: Stop and call emergency services now.
- Confusion, seizure, collapse or low glucose that does not recover: Get emergency help. Do not give food or drink to an unconscious person.
- A painful, hot, swollen injection site or spreading redness: Seek urgent same-day care; rapid breathing, faintness or severe illness needs emergency help.
Who should avoid it
- pregnant: Precaution: no pregnancy exposure, fetal safety or reproductive-toxicity data were found.
- breastfeeding: Precaution: transfer into milk and effects on a nursing infant are unknown.
- tryingToConceive: Precaution: fertility effects and a safe washout interval are unknown.
- under18: Precaution: no pediatric dosing or developmental safety studies were found.
- heartCondition: Human heart safety is unknown; a mouse heart-failure result cannot establish benefit or safety in people.
- uncontrolledBloodPressure: No human blood-pressure safety data. Heart-rate and faintness complaints appear in unverified reports.
- diabetes: Human glucose responses are unknown. Both higher and lower glucose have been reported online.
- kidneyDisease: Human clearance and dose adjustment are unknown; mouse kidney findings do not establish a kidney-safe dose.
- liverDisease: Human liver preparations break down the compound; exposure and dose adjustment with liver disease are unknown.
- activeCancer: No cancer safety studies in people were found. Effects on cell energy pathways do not establish cancer safety.
- surgeryPlanned: Tell the anesthesia team about use and all solvents. No evidence-based time to stop before surgery is known.
- testedAthlete: Prohibited at all times. Not being named in the 2026 list does not make an unapproved drug permitted.
- other: A previous serious allergic reaction to this product or its solvent should stop repeat exposure.
Interactions
- Insulin: Insulin can cause low glucose. Added SLU-PP-332 effects and insulin-adjustment rules have not been studied in people.
- Sulfonylureas: These drugs can cause low glucose. Added effects and dose-adjustment rules with SLU-PP-332 have not been studied in people.
- GLP-1 drugs and retatrutide: No human combination trial found. Users report lightheadedness and variable glucose during multi-drug use.
- Other ERR agonists: Same-target combinations have no human safety data. SLU-PP-915 is a different compound, not an oral version of SLU-PP-332.
- BAM15 and other experimental metabolic drugs: Online combinations add unstudied metabolic effects; no protective or safe stacking schedule is known.
- Piperine absorption boosters: Oil/piperine mixtures are proposed online to alter exposure. Neither absorption nor interaction risk has been measured in people.
- Warfarin and other anticoagulants: No interaction data exist. This is an uncertainty screen for drugs where exposure changes or injection bleeding matter, not a proven drug interaction.
Product quality risks
- Health Canada warns that unauthorized injectable drugs have not been assessed for safety, efficacy or quality. This is general product-risk evidence.
- Wrong identity, wrong amount, microbial contamination and unsafe excipients are risks of unauthorized drugs; their frequency for SLU-PP-332 is unknown.
- No independent retail-product survey or SLU-PP-332-specific poison-center dataset was found. Vendor certificates are not a substitute.
- Powder purity does not establish dose per capsule/vial, solvent safety, sterility or endotoxin levels.
- Cloudy or settled mixtures can have uncertain dose uniformity. A clear appearance also cannot prove injection quality.
Related to SLU-PP-332
- Tirzepatide: A weekly GIP/GLP-1 injection with strong diabetes and weight-loss evidence and common stomach side effects.
- Retatrutide: An experimental weekly injection with phase 3 weight-loss results.
- MOTS-c: A peptide the body makes; injection benefits and safety remain unproven.
- Tesamorelin: A peptide approved for deep abdominal fat in adults with HIV lipodystrophy.
- SS-31 (elamipretide): A peptide approved for Barth syndrome muscle strength; benefit needs confirmation and broader energy benefits remain unproven.
- 5-amino-1MQ: An experimental NNMT blocker with animal findings, no human dosing trials and uncertain risks.
Sources
- 2027 Prohibited List: Summary of Changes, UK Anti-Doping · 2026
- 21 CFR 216.23 — Bulk drug substances that can be used to compound drug products in accordance with section 503A of the Federal Food, Drug, and Cosmetic Act., Office of the Federal Register · eCFR · 2026
- 503B Bulk Drug Substances List, FDA · FDA · 2026
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act, FDA · FDA · 2026
- Bulk Drug Substances Used in Compounding Under Section 503A of the FD&C Act, FDA · FDA · 2026
- Cellulitis, NHS · NHS · 2026
- Medicines, European Medicines Agency · European Medicines Agency · 2026
- MHRA Products | Home, MHRA · MHRA · 2026
- Pyrogen and Endotoxins Testing: Questions and Answers, FDA · 2026
- The 2026 Prohibited List, World Anti-Doping Agency · WADA · 2026
- Therapeutic Goods (Poisons Standard—October 2026) Instrument 2026, Australian Government · 2026
- Think twice before injecting peptides bought online: unauthorized products can seriously harm you, Health Canada · Health Canada · 2026
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503B of the Federal Food, Drug, and Cosmetic Act, FDA · FDA · 2025
- Anaphylaxis, NHS · NHS · 2023
- Low blood sugar (hypoglycaemia), NHS · 2023
Sources checked: 2026-10-18.
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