What does Selank do? Benefits and evidence

A Russian nasal anxiety peptide with uncertain long-term benefit and safety.

Also called: Селанк, TP-7, Tuftsin-PGP, TKPRPGP.

Nootropic peptides · Tuftsin-derived peptide studied for anxiety and cognition.

Selank is a synthetic peptide used as a nasal anxiety medicine in Russia. Most small studies lacked placebo comparisons; lasting benefit and safety remain unclear. Some reports may reuse participants. Injected use has not been established.

  • In Russia, its nose drops are given to people for anxiety and stress-related symptoms; this is not an approved use in the US. (Studied in a trial)
  • In a small trial against a sedative anxiety drug, it caused less drowsiness, though anxiety scores fell a bit less. (Studied in a trial)
  • In a small study (15 vs 15 people) of adjustment problems, those taking it had lower symptom scores at day 28. (Studied in a trial)
  • People report calm focus and better productivity, often alongside Semax, though some notice no effect. (Reported by users)

Uses in the sources

  • Studied for generalized anxiety, neurasthenia and other anxiety disorders. Evidence is short-term and mostly from Russia. (Studied in a trial) (source)
  • Russian nasal instructions include anxiety, stress-related symptoms and adjustment problems. (Clinician-published) (source)
  • People report calm focus, better productivity or no effect, often with Semax. (Reported by users) (source)

Related to Selank

Sources

Sources checked: 2026-10-18.

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