How Selank works
A Russian nasal anxiety peptide with uncertain long-term benefit and safety.
Also called: Селанк, TP-7, Tuftsin-PGP, TKPRPGP.
Nootropic peptides · Tuftsin-derived peptide studied for anxiety and cognition.
Selank is based on tuftsin, a small immune signal, with an added stabilizing tail. Laboratory studies suggest effects on GABA signaling and peptide breakdown. How these changes explain anxiety relief in people is uncertain.
- GABA receptor signaling: Modified GABA binding in rat brain membrane assays.
- Enkephalin-degrading enzymes: Slowed peptide breakdown in laboratory plasma assays.
- Immune signals: Changed cytokine measurements in a small clinical report.
Half-life: No reliable human elimination half-life was verified.
Related to Selank
- Semax: A Russian nasal peptide with limited human evidence for brain and nerve effects.
- PE-22-28: An experimental mood peptide studied in mice, with no human trials found.
- Dihexa: An experimental memory compound with disputed animal research and no established human dose.
- P21: An experimental memory peptide with animal research and no established human dose or safety profile.
- Cerebrolysin: An injectable pig brain mixture with mixed stroke, brain-injury and dementia evidence.
Sources
- 503B Bulk Drug Substances List, FDA · FDA · 2026
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act, FDA · FDA · 2026
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks, FDA · FDA · 2026
- MHRA Products | Home, MHRA · MHRA · 2026
- The Prohibited List, World Anti-Doping Agency · World Anti-Doping Agency · 2026
- Therapeutic Goods (Poisons Standard—October 2026) Instrument 2026, Australian Government · Australian Government · 2026
- Think twice before injecting peptides bought online: unauthorized products can seriously harm you, Health Canada · Health Canada · 2026
- Anaphylaxis, NHS · NHS · 2023
- Australian Register of Therapeutic Goods (ARTG), Therapeutic Goods Administration · TGA
- Search, European Medicines Agency
- Semax-Related Bulk Drug Substances: Semax (Free Base) and Semax Acetate
- Symptoms of a stroke
- Селанк® | ЛП-№(010951)-(РГ-RU) | ГРЛС 2026
- POST-COVID SYNDROME, POSSIBILITIES FOR THERAPY OF ASTHENIC DISORDERS WITH SELANK, 2024
- Functional Connectomic Approach to Studying Selank and Semax Effects., Panikratova YR et al. · Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2020
Sources checked: 2026-10-18.
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