What does GHK-Cu do? Benefits and evidence

A copper-binding skin peptide with small topical studies and untested systemic injections.

Also called: Copper tripeptide-1, Glycyl-L-histidyl-L-lysine copper, Copper-GHK.

Healing and repair peptides · Copper-binding tripeptide complex.

GHK-Cu is a small peptide bound to copper. It is studied in skin creams, wound gels and eyebrow serum, with mixed results from small human studies. People also inject it for skin, hair and recovery, but no verified human trial establishes a systemic injection dose. Copper handling, local reactions and product contamination matter.

  • In small studies, face serums and creams with it improved wrinkles and skin appearance, though results are mixed. (Studied in a trial)
  • In a small study, a 2% serum on sparse eyebrows modestly raised hair count at 12 weeks. (Studied in a trial)
  • In one trial, a gel helped diabetic foot ulcers close, but other wound studies disagree. (Studied in a trial)
  • People report skin changes from injecting it and less hair loss from scalp use; others report no effect. (Reported by users)

Uses in the sources

  • Studied topically for wrinkles and sparse eyebrows. Small trials show mixed results; they do not establish a benefit from systemic injections. (Studied in a trial) (source)
  • Topical wound results disagree. Early diabetic-ulcer subgroups improved; venous ulcers did not. A later phase 3 failure was reported in trade press. (Studied in a trial) (source)
  • People report injecting it for skin and hair changes. These uncontrolled reports cannot establish benefit or long-term safety. (Reported by users) (source)
  • Users combine it with BPC-157, TB-500 or KPV for recovery. These injection combinations have no controlled human evidence. (Reported by users) (source)

Related to GHK-Cu

Sources

Sources checked: 2026-10-18.

Information only, not medical advice. Peptifacts does not sell anything and does not link to sellers.