GHK-Cu dosage: reported doses and schedule

A copper-binding skin peptide with small topical studies and untested systemic injections.

Also called: Copper tripeptide-1, Glycyl-L-histidyl-L-lysine copper, Copper-GHK.

Healing and repair peptides · Copper-binding tripeptide complex.

Typical reported dose: 2 mg once a day at bedtime

  • Venous ulcers: 0.4% cream: 0.4% copper-tripeptide cream once daily, on the skin. Studied in a trial. Studied in: Adults with venous ulcers under standard wound care. (source)
  • Diabetic ulcers: 2% gel: 2% GHK-Cu gel after initial sharp debridement once daily, on the skin. Studied in a trial. Studied in: Adults with diabetic neuropathic ulcers. (source)
  • Facial cream: 12 weeks: GHK-Cu facial cream; strength and amount unavailable twice daily, on the skin. Studied in a trial. Studied in: 71 women with sun-related skin aging. (source)
  • Eye cream: 12 weeks: GHK-Cu eye cream; strength and amount unavailable twice daily, on the skin. Studied in a trial. Studied in: 41 women with sun-related skin aging. (source)
  • Facial cream: chapter report: GHK-Cu facial cream; strength and amount unavailable twice daily, on the skin. Studied in a trial. Studied in: 67 women aged 50–59. (source)
  • Carrier-based facial serum: GHK-Cu lipid-nanocarrier serum; strength and amount not reported twice daily, morning and evening, on the skin. Studied in a trial. Studied in: Women aged 40–65. (source)

Highest studied: 2% gel once daily was used in a diabetic-ulcer trial; scalp exposure is not comparable..

These are doses reported in labels, trials or user reports, not a personal plan. Check the source behind each one.

Work out syringe units with the dosing calculator

Related to GHK-Cu

Sources

Sources checked: 2026-10-18.

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