DSIP dosage: reported doses and schedule

An experimental sleep peptide with small, mixed human studies and no FDA-approved dose.

Also called: Delta sleep-inducing peptide, Delta-sleep-inducing peptide, Emideltide.

Sleep peptides · Experimental nine-amino-acid peptide with uncertain sleep-signaling targets.

Typical reported dose: 500 mcg at bedtime

  • Morning infusion: 25 nmol/kg: 25 nmol/kg IV over 20 minutes one infusion on the active crossover day, into a vein. Studied in a trial. Studied in: Six healthy adults, four men and two women. (source)
  • Bedtime crossover: 25 nmol/kg: 25 nmol/kg IV over 4 minutes on active nights in P-D-P or D-P-D sequence, into a vein. Studied in a trial. Studied in: Six middle-aged adults with chronic insomnia. (source)
  • Single evening infusion: 25 nmol/kg IV over 4 minutes single dose, into a vein. Studied in a trial. Studied in: Healthy volunteers and adults with insomnia in five small experiments. (source)
  • Four evening infusions: 25 nmol/kg IV over 4 minutes on four evenings once daily for four consecutive evenings, into a vein. Studied in a trial. Studied in: Healthy volunteers and adults with insomnia in five small experiments. (source)
  • Six morning infusions: 25 nmol/kg IV on six consecutive mornings once daily for six mornings, into a vein. Studied in a trial. Studied in: Healthy volunteers and adults with insomnia in five small experiments. (source)
  • Seven nights: 30 nmol/kg: 30 nmol/kg IV each night on laboratory nights 3-9 once nightly for seven consecutive nights, into a vein. Studied in a trial. Studied in: 14 middle-aged adults with chronic insomnia. (source)

These are doses reported in labels, trials or user reports, not a personal plan. Check the source behind each one.

Work out syringe units with the dosing calculator

Related to DSIP

Sources

Sources checked: 2026-10-18.

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