Thymogen results: what to expect and when
A Russian peptide used for immune problems, with negative cancer trials.
Also called: Timogen, Thymagen, L-Glu-L-Trp, Glu-Trp, EW, Alpha-glutamyl-tryptophan, Oglufanide, IM862, IM-862.
Khavinson bioregulator peptides · Synthetic L-glutamyl-L-tryptophan immune-modulating dipeptide.
Controlled IM862 cancer trials found no clear benefit. The 59 human records include trial registrations, incomplete reports and stomach studies that reuse participants.
Key studies
- Kaposi sarcoma: two nasal schedules: Early responses were not confirmed in the later placebo-controlled trial. (source)
- Kaposi sarcoma: negative phase 3: IM862 did not beat placebo and may have accelerated progression. (source)
- Kidney cancer: no tumor responses: High nasal doses produced no objective cancer responses. (source)
- Prostate cancer: no clear benefit: IM862 did not prolong time to PSA progression. (source)
- Before abdominal cancer surgery: Fewer complications were reported, with important reporting errors. (source)
- Skin and soft-tissue wound trial: A small blinded trial reported faster wound healing. (source)
Related to Thymogen
- Epitalon: A peptide with telomerase effects in cells, but no proof that people live longer.
- Pinealon: A peptide with unproven brain benefits and no established injection dose.
- Thymalin: A calf thymus extract studied for immune problems, with uncertain safety and product identity.
- Vesugen: An experimental blood-vessel peptide with unclear benefits and poorly defined safety.
- Cortagen: A four-amino-acid brain peptide backed mainly by animal work and unverified patent claims.
- BPC-157: An experimental repair peptide with mostly animal evidence and a few small human reports.
Sources
- Bulk Drug Substances Used in Compounding, FDA · 2026
- Medicines, European Medicines Agency · European Medicines Agency · 2026
- MHRA Products | Home, MHRA · MHRA · 2026
- Pyrogen and Endotoxins Testing: Questions and Answers, FDA · 2026
- TGA warning on the risks of importing unapproved peptide products, Therapeutic Goods Administration · 2026
- The 2026 Prohibited List, World Anti-Doping Agency · WADA · 2026
- Darmerica, LLC - 716152 - 12/08/2025, FDA · FDA · 2025
- Инструкция по медицинскому применению лекарственного препарата Регастим Гастро, Министерство здравоохранения Российской Федерации · 2023
- Тимоген р-р для в/м инъекций - Цитомед - инструкция по применению, 2023
- Тимоген спрей - Цитомед - инструкция по применению, 2011
- Тимоген: крем для наружного применения. Инструкция по медицинскому применению препарата, 2007
- Q6A Specifications: Test Procedures and Acceptance Criteria for New Drug Substances and New Drug Products: Chemical Substances, FDA · FDA · 2000
- Drug Product Database online query
- OGLUFANIDE SODIUM
- Alpha-glutamyl-tryptophan as adjuvant reparative therapy after Helicobacter pylori eradication in chronic atrophic gastritis: A case report and literature review, 2026
Sources checked: 2026-10-18.
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