Semax dosage: reported doses and schedule

A Russian nasal peptide with limited human evidence for brain and nerve effects.

Also called: Семакс, ACTH(4–7)-PGP, MEHFPGP.

Nootropic peptides · ACTH-fragment analogue studied for brain and nerve effects.

Typical reported dose: 400–900 mcg a day as nose drops, before midday

  • Acute stroke: 12 mg/day: 12 mg/day daily total; within-day split not stated, nasal spray. Studied in a trial. Studied in: Moderate acute ischemic stroke. (source)
  • Acute stroke: 18 mg/day: 18 mg/day daily total; within-day split not stated, nasal spray. Studied in a trial. Studied in: Severe acute ischemic stroke. (source)
  • Two courses of 12 mg/day: 12 mg/day on days 1–10 only, then No Semax on days 11–24, then 12 mg/day on days 25–34 only daily total; within-day split not stated, nasal spray. Studied in a trial. Studied in: Adults with motor neuron disease. (source)
  • Two courses of 6 mg/day: 6 mg/day on days 1–10 only, then No Semax on days 11–30, then 6 mg/day on days 31–40 only daily total; within-day split not stated, nasal spray. Studied in a trial. Studied in: Adults after ischemic stroke. (source)
  • Psoriasis study: 600 mcg/day: 600 mcg/day as 0.1% nasal solution daily total; within-day split not stated, nasal spray. Studied in a trial. Studied in: Psoriasis with metabolic syndrome. (source)
  • Early attention study: one dose: 0.25 mg intranasally once once only, nasal spray. Studied in a trial. Studied in: Healthy adult men. (source)

These are doses reported in labels, trials or user reports, not a personal plan. Check the source behind each one.

Work out syringe units with the dosing calculator

Related to Semax

Sources

Sources checked: 2026-10-18.

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