Ipamorelin research: studies, doses and safety
An experimental peptide that triggers growth hormone release.
Also called: NNC 26-0161, NNC-26-0161.
Growth hormone secretagogues (ghrelin receptor) · Ghrelin receptor agonist and growth hormone secretagogue.
A bowel-surgery trial used IV infusions twice daily for up to seven days or until discharge; this does not define a home-injection course.
Five human research records, two from registries only, plus two reports to FDA. The published bowel-surgery trial found no clear benefit; a review includes the same trial.
Key studies
- First human IV dose study: IV ipamorelin produced a brief GH pulse; it did not test a chronic wellness regimen. (source)
- Bowel surgery: 0.03 mg/kg: The main and secondary efficacy analyses did not show a significant benefit. (source)
- Second bowel-surgery trial: A larger completed dose-finding trial remains a major unpublished-results gap. (source)
- Nasal exposure for doping analysis: This documents human nasal exposure, not a clinical-use schedule. (source)
- Veterans: mixed-treatment cohort: A registered mixed-treatment cohort provides no isolated ipamorelin outcome evidence. (source)
- Nasal headache report: Headache and watery eyes; product quality was questioned. (source)
Related to Ipamorelin
- MK-677 (ibutamoren): This experimental oral drug raises growth hormone and IGF-1; risks include high blood sugar and swelling.
- GHRP-2: A peptide that releases growth hormone and can increase hunger.
- GHRP-6: A peptide studied in growth hormone tests and an experimental stroke combination.
- Hexarelin: A peptide that releases growth hormone; repeated use can weaken the response.
- Tirzepatide: A weekly GIP/GLP-1 injection with strong diabetes and weight-loss evidence and common stomach side effects.
- BPC-157: An experimental repair peptide with mostly animal evidence and a few small human reports.
Sources
- 503B Bulk Drug Substances List, FDA · FDA · 2026
- Bulk Drug Substances Used in Compounding Under Section 503A of the FD&C Act, FDA · FDA · 2026
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks, FDA · FDA · 2026
- Find product information about medicines, Medicines and Healthcare products Regulatory Agency · MHRA · 2026
- Peptide products, Therapeutic Goods Administration · TGA · 2026
- The 2026 Prohibited List, World Anti-Doping Agency · WADA · 2026
- Therapeutic Goods (Poisons Standard—October 2026) Instrument 2026, Australian Government · Australian Government · 2026
- Think twice before injecting peptides bought online: unauthorized products can seriously harm you, Health Canada · Health Canada · 2026
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503B of the Federal Food, Drug, and Cosmetic Act, FDA · FDA · 2025
- GENOTROPIN® (somatropin) for injection, for subcutaneous use, FDA · 2025
- 注射用GHRP科研100, PMDA · 2025
- October 29, 2024 Meeting of the Pharmacy Compounding Advisory Committee, FDA · 2024
- October 29, 2024 Meeting of the Pharmacy Compounding Advisory Committee, FDA · 2024
- October 29, 2024 Pharmacy Compounding Advisory Committee (PCAC) Meeting, FDA · 2024
- Using intramuscular injections in people on oral anticoagulants, NHS Specialist Pharmacy Service · NHS Specialist Pharmacy Service · 2023
Sources checked: 2026-10-18.
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