How to reconstitute VIP: mixing and storage

Comes as: Community reports describe freeze-dried powder vials and nasal spray bottles., Published nasal studies used a prepared liquid; this does not validate home-made products..

Mixed with: Users report bacteriostatic water. The 2017 study used sterile saline plus 1% glycerin; these preparations are not interchangeable..

Common vial sizes: 5, 10 mg. Common water amounts: 2, 10 mL.

• One forum example mixed 5 or 10 mg into 10 mL total, assuming a 0.1 mL spray. Actual spray delivery and drug content were untested.
• The same report used 2 mL first, then 8 mL more. These are community practices, not validated compounding instructions.
• Bacteriostatic water does not establish sterility, nasal compatibility or product shelf life.
• The 2017 study reported 500 mcg/mL, delivering 50 mcg per 0.1 mL spray. Its device and formulation were controlled.

Before mixing: A validated shelf life and storage temperature for unverified powder vials were not found.

After mixing: Home-mixed VIP has no verified stability or sterility period. The 2017 study’s refrigerated 60-day limit applied to its specific nasal formulation.