Oxytocin dosage: reported doses and schedule

A hormone used during childbirth; nasal social and weight-loss benefits remain unproven.

Also called: Pitocin, Syntocinon, OT, OXT, TTA-121.

Neuropeptides · Oxytocin-receptor agonist and uterotonic hormone · Evidence: Approved drug.

Typical reported dose: 25–100 mcg per injection, timing varies

  • Pitocin: supervised labour infusion: Start 0.5–1 mU/min; increase by 1–2 mU/min every 30–60 minutes to the desired contraction pattern., then At 5–6 cm dilation, the rate may be reduced by similar increments. continuous infusion; adjust every 30–60 minutes, into a vein. Drug label. Studied in: Hospital obstetric patients. (source)
  • Pitocin: bleeding after birth, IV: 10–40 units added to the running IV fluid; maximum 40 units per 1000 mL. Adjust rate to control uterine atony. continuous infusion adjusted to uterine response, into a vein. Drug label. Studied in: Hospital postpartum patients. (source)
  • Pitocin: bleeding after birth, IM: 10 units (1 mL) intramuscularly after delivery of the placenta. one dose after delivery of the placenta, into muscle. Drug label. Studied in: Postpartum patients after placental delivery. (source)
  • Pitocin: infusion after curettage: 10 units in 500 mL physiologic saline or 5% dextrose-in-water to support uterine contraction after curettage. infusion; rate individualized, into a vein. Drug label. Studied in: Patients after curettage for incomplete, inevitable or elective abortion. (source)
  • Pitocin: midtrimester abortion infusion: 10–20 milliunits/minute; total dose must not exceed 30 units in 12 hours. continuous infusion; total capped over 12 hours, into a vein. Drug label. Studied in: Patients after intra-amniotic treatment for midtrimester abortion. (source)
  • WHO: prevent bleeding after birth: 10 IU intramuscularly for postpartum-haemorrhage prevention. one preventive dose, into muscle. Clinician-published. Studied in: Women giving birth under skilled care. (source)

Highest studied: Highest located daily human regimen: 2.5 IU/day, about 4.2 mcg, in a weak 1953 engorgement trial..

These are doses reported in labels, trials or user reports, not a personal plan. Check the source behind each one.

Work out syringe units with the dosing calculator

Sources

Sources checked: 2026-10-18.

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