GHRP-6 research: studies, doses and safety
A peptide studied in growth hormone tests and an experimental stroke combination.
Also called: Growth hormone-releasing hexapeptide, SKF-110679.
Growth hormone secretagogues (ghrelin receptor) · Ghrelin receptor agonist and growth hormone secretagogue.
The phase 3 stroke study tested GHRP-6 with EGF. Its phase cannot be assigned to GHRP-6 alone. A direct-administration study count is not established here.
Key studies
- Early human dose finding: A brief IV infusion produced a dose-related GH rise. (source)
- Placebo-controlled GH dose response: The dose-response and acute GHRH interaction do not prove long-term muscle benefits. (source)
- Nasal dose and repeated-dose study: Nasal administration produced a hormone response in a very small study. (source)
- Early oral dose comparison: Oral GHRP-6 was active at much larger doses than IV exposure. (source)
- 34-hour IV infusion: A prolonged infusion maintained GH activity, but clinical benefit was not studied. (source)
- GH responses in obesity: A larger GH response in obesity does not establish fat-loss efficacy. (source)
Related to GHRP-6
- Ipamorelin: An experimental peptide that triggers growth hormone release.
- MK-677 (ibutamoren): This experimental oral drug raises growth hormone and IGF-1; risks include high blood sugar and swelling.
- GHRP-2: A peptide that releases growth hormone and can increase hunger.
- Hexarelin: A peptide that releases growth hormone; repeated use can weaken the response.
- Sermorelin: An experimental short-acting peptide that triggers growth hormone release, with limited evidence of adult benefits.
Sources
- 503B Bulk Drug Substances List, FDA · FDA · 2026
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act, FDA · FDA · 2026
- Bulk Drug Substances Used in Compounding Under Section 503A of the FD&C Act, FDA · FDA · 2026
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks, FDA · FDA · 2026
- Find product information about medicines, Medicines and Healthcare products Regulatory Agency · MHRA · 2026
- Peptide products, Therapeutic Goods Administration · TGA · 2026
- The 2026 Prohibited List, World Anti-Doping Agency · WADA · 2026
- Therapeutic Goods (Poisons Standard—October 2026) Instrument 2026, Australian Government · Australian Government · 2026
- Think twice before injecting peptides bought online: unauthorized products can seriously harm you, Health Canada · Health Canada · 2026
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503B of the Federal Food, Drug, and Cosmetic Act, FDA · FDA · 2025
- GENOTROPIN® (somatropin) for injection, for subcutaneous use, FDA · 2025
- 注射用GHRP科研100, PMDA · 2025
- October 29, 2024 Meeting of the Pharmacy Compounding Advisory Committee, FDA · 2024
- Using intramuscular injections in people on oral anticoagulants, NHS Specialist Pharmacy Service · NHS Specialist Pharmacy Service · 2023
- Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline., Molitch ME et al. · The Journal of clinical endocrinology and metabolism · 2011
Sources checked: 2026-10-18.
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