What does Cerebrolysin do? Benefits and evidence
An injectable pig brain mixture with mixed stroke, brain-injury and dementia evidence.
Also called: FPF-1070, Cerebrolysin concentrate.
Nootropic peptides · Porcine brain-derived peptide and amino-acid mixture · Evidence: Approved drug.
Cerebrolysin is an injectable mix of pig brain peptides and amino acids, with mixed recovery results and uncertain healthy-person benefits and long-term safety. Cochrane found no survival benefit after acute stroke and a possible rise in serious nonfatal harms. Some stroke and brain-injury trials report gains. National approvals exist in parts of Europe and Asia, but no FDA approval.
- In Austria, doctors use it for patients after a stroke or head injury and for some kinds of dementia; it is not FDA approved. (Studied in a trial)
- In stroke rehab trials, people's arm recovery was better with it, though the gain was smaller when trials were pooled. (Studied in a trial)
- After brain injury, a trial found a small gain in daily function and thinking, but the evidence rests on two small trials. (Studied in a trial)
- People report better mood, memory or sleep and less anxiety, though these goals lack strong clinical evidence. (Reported by users)
Uses in the sources
- Nationally approved in Austria for support after stroke and head injury, and for Alzheimer-type or vascular dementia. (Clinician-published) (source)
- Studied alongside stroke rehabilitation and standard TBI care; results differ across trials. (Studied in a trial) (source)
- Reported online for memory, mood and recovery from past substance use; these goals lack convincing clinical evidence. (Reported by users) (source)
Related to Cerebrolysin
- Semax: A Russian nasal peptide with limited human evidence for brain and nerve effects.
- Selank: A Russian nasal anxiety peptide with uncertain long-term benefit and safety.
- PE-22-28: An experimental mood peptide studied in mice, with no human trials found.
- Dihexa: An experimental memory compound with disputed animal research and no established human dose.
- P21: An experimental memory peptide with animal research and no established human dose or safety profile.
- BPC-157: An experimental repair peptide with mostly animal evidence and a few small human reports.
Sources
- 21 CFR 216.23 — Bulk drug substances that can be used to compound drug products in accordance with section 503A of the Federal Food, Drug, and Cosmetic Act., Office of the Federal Register · eCFR · 2026
- 503B Bulk Drug Substances List, FDA · FDA · 2026
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act, FDA · FDA · 2026
- Bulk Drug Substances Used in Compounding Under Section 503A of the FD&C Act, FDA · FDA · 2026
- MHRA Products | Home, MHRA · MHRA · 2026
- TGA strengthens compliance focus on unapproved peptide products as part of evolving risk response, Therapeutic Goods Administration · TGA · 2026
- The 2026 Prohibited List, World Anti-Doping Agency · WADA · 2026
- Therapeutic Goods (Poisons Standard—October 2026) Instrument 2026, Australian Government · Australian Government · 2026
- Using intramuscular injections in people on oral anticoagulants, NHS Specialist Pharmacy Service · NHS Specialist Pharmacy Service · 2023
- European Academy of Neurology and European Federation of Neurorehabilitation Societies guideline on pharmacological support in early motor rehabilitation after acute ischaemic stroke., Beghi E et al. · European journal of neurology · 2021
- Tailor Made Compounding LLC - 594743 - 04/01/2020, FDA · FDA · 2020
- Q6A Specifications: Test Procedures and Acceptance Criteria for New Drug Substances and New Drug Products: Chemical Substances, FDA · FDA · 2000
- CEREBROLYSIN, BASG
- Drug Product Database online query, Health Canada
- PHARMACY & POISONS BOARD OF HONG KONG | 香港藥劑業及毒藥管理局, Hong Kong Department of Health
Sources checked: 2026-10-18.
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