CagriSema dosage: reported doses and schedule

Typical reported dose: 0.25 mg of each drug weekly to start, up to 2.4 mg of each

• Phase 2: 2.4 mg of each: 0.25 mg of each drug once weekly, then 0.5 mg of each drug once weekly, then 1 mg of each drug once weekly, then 1.7 mg of each drug once weekly once weekly, under the skin. Studied in a trial. Studied in: Adults with type 2 diabetes and BMI ≥27 on metformin, with or without an SGLT2 inhibitor. (source)
• REDEFINE 1: 2.4 mg of each: 0.25 mg of each drug once weekly, then 0.5 mg of each drug once weekly, then 1 mg of each drug once weekly, then 1.7 mg of each drug once weekly once weekly, under the skin. Studied in a trial. Studied in: Adults without diabetes: BMI ≥30, or ≥27 with a weight-related condition. (source)
• REDEFINE 2: 2.4 mg of each: 0.25 mg of each drug once weekly, then 0.5 mg of each drug once weekly, then 1 mg of each drug once weekly, then 1.7 mg of each drug once weekly once weekly, under the skin. Studied in a trial. Studied in: Adults with type 2 diabetes, BMI ≥27 and HbA1c 7–10%. (source)
• REDEFINE 5: 2.4 mg of each: 0.25 mg of each drug once weekly, then 0.5 mg of each drug once weekly, then 1 mg of each drug once weekly, then 1.7 mg of each drug once weekly once weekly, under the skin. Studied in a trial. Studied in: Adults with high BMI and weight-related complications; 24% had type 2 diabetes. (source)
• REIMAGINE 1: 2.4 mg of each: 0.25 mg of each drug once weekly, then 0.5 mg of each drug once weekly, then 1 mg of each drug once weekly, then 1.7 mg of each drug once weekly once weekly, under the skin. Studied in a trial. Studied in: Adults with type 2 diabetes inadequately controlled by diet and exercise. (source)
• REIMAGINE 3: 2.4 mg of each: 0.25 mg of each drug once weekly, then 0.5 mg of each drug once weekly, then 1 mg of each drug once weekly, then 1.7 mg of each drug once weekly once weekly, under the skin. Studied in a trial. Studied in: Adults with type 2 diabetes on daily basal insulin, with or without metformin. (source)

These are doses reported in labels, trials or user reports, not a personal plan. Check the source behind each one.

Work out syringe units with the dosing calculator