What does Adipotide do? Benefits and evidence

A fat-blood-vessel targeting peptide with monkey weight-loss data and kidney toxicity.

Also called: FTPP, FTTP, Prohibitin-TP01, Prohibitin-targeting peptide 1, CKGGRAKDC-GG-D(KLAKLAK)2.

Fat-loss peptides · Prohibitin-targeted proapoptotic peptidomimetic.

Adipotide is designed to destroy blood vessels that feed white fat. It reduced weight in rodents and monkeys, but also injured monkey kidneys. One human phase 1 trial enrolled four men and ended without posted results. It has no FDA approval or established human dosing schedule. Online use reports cannot show that it works or is safe.

  • In animal studies in monkeys, it reduced body fat and weight. (animal)
  • In animal studies in rodents, most of the weight loss came from eating less. (animal)
  • In obese mice, blood sugar handling improved even before weight came off. (animal)
  • A few people report fat loss, but often while dieting or taking other weight-loss drugs, so the cause is unclear. (Reported by users)

Uses in the sources

  • People report using it for fat loss. Published efficacy data are from animals; the human trial has no results. (Reported by users) (source)
  • Registered for dose-finding in men with metastatic prostate cancer and obesity; no cancer or weight outcomes were reported. (Studied in a trial) (source)

Related to Adipotide

Sources

Sources checked: 2026-10-18.

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