Semaglutide dosage: reported doses and schedule

A GLP-1 medicine with strong weight, glucose, heart and kidney evidence; dose and formulation matter.

Also called: Ozempic, Wegovy, Wegovy HD, Wegovy FlexTouch, Rybelsus, oral semaglutide, NN9535, NN9924.

GLP-1 / GIP / glucagon agonists · GLP-1 receptor agonist · Evidence: Approved drug.

Typical reported dose: 0.25 mg once a week to start, up to 2.4 mg

  • Ozempic injection: 0.5–2 mg: 0.25 mg once weekly, then 0.5 mg once weekly, then 1 mg once weekly, then 2 mg once weekly once weekly, under the skin. Drug label. Studied in: Adults in the product’s approved population. (source)
  • Ozempic: kidney-risk indication: 0.25 mg once weekly, then 0.5 mg once weekly, then 1 mg once weekly once weekly, under the skin. Drug label. Studied in: Adults with diabetes and chronic kidney disease. (source)
  • Wegovy: weight maintenance: 0.25 mg once weekly, then 0.5 mg once weekly, then 1 mg once weekly, then 1.7 mg once weekly once weekly, under the skin. Drug label. Studied in: Adults in the product’s approved population. (source)
  • Wegovy: cardiovascular risk: 0.25 mg once weekly, then 0.5 mg once weekly, then 1 mg once weekly, then 1.7 mg once weekly once weekly, under the skin. Drug label. Studied in: Adults in the product’s approved population. (source)
  • Wegovy: noncirrhotic MASH: 0.25 mg once weekly, then 0.5 mg once weekly, then 1 mg once weekly, then 1.7 mg once weekly once weekly, under the skin. Drug label. Studied in: Adults in the product’s approved population. (source)
  • Wegovy: 1.7 mg maintenance: 0.25 mg once weekly, then 0.5 mg once weekly, then 1 mg once weekly, then 1.7 mg once weekly once weekly, under the skin. Drug label. Studied in: Adults in the product’s approved population. (source)

Highest studied: Highest verified human weekly arm: 16 mg nominal, 16.13 mg delivered; approved limits are lower.; Highest verified daily oral efficacy dose: 50 mg; also EU-labeled for diabetes..

These are doses reported in labels, trials or user reports, not a personal plan. Check the source behind each one.

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Related to Semaglutide

Sources

Sources checked: 2026-10-18.

Information only, not medical advice. Peptifacts does not sell anything and does not link to sellers.