Orforglipron dosage: reported doses and schedule

Typical reported dose: 0.8 mg once a day to start, up to 17.2 mg

• FDA tablets: at least 30 days per step: 0.8 → 2.5 → 5.5 → 9 → 14.5 → 17.2 mg daily; at least 30 days per step. Steps above 5.5 mg depend on response and tolerability. once daily, by mouth. Drug label. Studied in: Adults with obesity, or overweight plus a weight-related condition. (source)
• ATTAIN-1: 6 mg capsules: 1 mg once daily, then 3 mg once daily, then 6 mg once daily once daily, by mouth. Studied in a trial. Studied in: Adults in ATTAIN-1: weight without diabetes. (source)
• ATTAIN-1: 12 mg capsules: 1 mg once daily, then 3 mg once daily, then 6 mg once daily, then 12 mg once daily once daily, by mouth. Studied in a trial. Studied in: Adults in ATTAIN-1: weight without diabetes. (source)
• ATTAIN-1: 36 mg capsules: 1 mg once daily, then 3 mg once daily, then 6 mg once daily, then 12 mg once daily once daily, by mouth. Studied in a trial. Studied in: Adults in ATTAIN-1: weight without diabetes. (source)
• ATTAIN-2: 6 mg capsules: 1 mg once daily, then 3 mg once daily, then 6 mg once daily once daily, by mouth. Studied in a trial. Studied in: Adults in ATTAIN-2: weight with diabetes. (source)
• ATTAIN-2: 12 mg capsules: 1 mg once daily, then 3 mg once daily, then 6 mg once daily, then 12 mg once daily once daily, by mouth. Studied in a trial. Studied in: Adults in ATTAIN-2: weight with diabetes. (source)

These are doses reported in labels, trials or user reports, not a personal plan. Check the source behind each one.

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