Melanotan II dosage: reported doses and schedule
An unapproved tanning peptide with small human trials and reports of serious harm.
Also called: Melanotan-2, MT-II, MT2, MT-2.
Melanocortin agonists · Nonselective melanocortin receptor agonist.
Typical reported dose: 250–500 mcg once a day for 2 weeks, then three times a week
- Pilot: five weight-based doses: Start 0.01 mg/kg SC; increase active doses by 0.005 mg/kg, to 0.03 mg/kg in two men and 0.025 mg/kg in one. every other weekday; five active doses over 2 weeks, under the skin. Studied in a trial. Studied in: Three monitored healthy adult men. (source)
- Erection study: 0.025 mg/kg: 0.025 mg/kg subcutaneously at each active visit. single monitored study-visit doses, under the skin. Studied in a trial. Studied in: Adult men with erection problems. (source)
- Organic ED: 0.025 mg/kg: 0.025 mg/kg subcutaneously at each active visit. single monitored study-visit doses, under the skin. Studied in a trial. Studied in: Adult men with erection problems. (source)
- Reported 250-to-500 mcg loading: 250 mcg SC daily for the first week., then 500 mcg SC daily for the second week., then 500 mcg SC on Monday, Wednesday and Friday. daily for 2 weeks, then three times weekly, under the skin. Reported by users, common report. Studied in: Adults reporting cosmetic tanning use. (source)
- Reported 20–100 mcg use: 20–100 mcg SC per reported dose. daily initially; some later use every few days or weekly, under the skin. Reported by users, occasional report. Studied in: Adults reporting cosmetic tanning use. (source)
- Reported weekly maintenance: 250 mcg SC once weekly. once weekly, under the skin. Reported by users, common report. Studied in: Adults reporting cosmetic tanning use. (source)
These are doses reported in labels, trials or user reports, not a personal plan. Check the source behind each one.
Related to Melanotan II
- Bremelanotide: An as-needed injection for low libido before menopause; nausea is common.
- Melanotan I / Afamelanotide: The molecule in an approved EPP implant; online tanning powder is a different formulation.
- Setmelanotide: A daily injection approved for specific genetic obesity and acquired hypothalamic obesity.
- Retatrutide: An experimental weekly injection with phase 3 weight-loss results.
- GHK-Cu: A copper-binding skin peptide with small topical studies and untested systemic injections.
Sources
- 503B Bulk Drug Substances List, FDA · FDA · 2026
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act, US Food and Drug Administration · 2026
- Bulk Drug Substances Used in Compounding Under Section 503A of the FD&C Act, FDA · FDA · 2026
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks, FDA · FDA · 2026
- Compounding and the FDA: Questions and Answers, FDA · FDA · 2026
- Meeting of the Pharmacy Compounding Advisory Committee, FDA · 2026
- Melanotan II tanning peptide products found to be inconsistently dosed, 2026
- Scenesse, 2026
- Scenesse, INN-afamelanotide, 2026
- The 2026 Prohibited List, World Anti-Doping Agency · WADA · 2026
- Therapeutic Goods (Poisons Standard—October 2026) Instrument 2026, Australian Government · Australian Government · 2026
- Don’t risk using tanning products containing melanotan, 2025
- Written questions and answers - Written questions, answers and statements - UK Parliament, 2025
- Priapism (painful erections) - NHS, NHS · 2023
- Notice of Opportunity for Hearing (NOOH) Manookian, Edward 8/5/16, 2016
Sources checked: 2026-10-18.
Information only, not medical advice. Peptifacts does not sell anything and does not link to sellers.