What does Hexarelin do? Benefits and evidence

A peptide that releases growth hormone; repeated use can weaken the response.

Also called: Examorelin, HEX, EP-23905, MF-6003.

Growth hormone secretagogues (ghrelin receptor) · Ghrelin receptor agonist and growth hormone secretagogue.

Hexarelin releases growth hormone and can raise prolactin and cortisol. Small studies tested injections, oral doses and nasal use. Repeated dosing can weaken the GH response. A 16-week study found no significant body-composition benefit. Acute heart effects do not establish treatment benefit or safety for chronic use.

  • In small studies, it raised growth hormone, but the effect weakened with repeated use. (Studied in a trial)
  • Small short-term studies found brief changes in heart pumping; lasting heart benefits were not shown. (Studied in a trial)
  • In a very small study of children, growth speed stayed above their starting level as the hormone effect faded. (Studied in a trial)

Uses in the sources

  • Studied to trigger GH release and explore GH-deficiency testing; this is not an approved treatment schedule. (Studied in a trial) (source)
  • Small acute studies examined heart pumping function; lasting heart-disease benefits were not established. (Studied in a trial) (source)
  • A 16-week SC study found no significant change in lean mass, body fat or bone density. (Studied in a trial) (source)
  • A seven-person nighttime study reduced deep sleep despite raising GH. (Studied in a trial) (source)

Related to Hexarelin

Sources

Sources checked: 2026-10-18.

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